The Guggenheim Museum is one of the last structures that Wright designed before his death in 1959. It is the culmination of decades of innovations throughout his architectural career, and shows the progression of his designs from linear to circular. The form of the building is part of Wright's continuing crusade to counteract the right angles that typically dominate architecture. The floor plan is not divided into individual floors connected by staircases or elevators, but is instead one single fluid ramp spiraling up six stories and resembling the inside of a seashell. A skylight illuminates the interior from above, and the white concrete walls reflect the light.

This beautiful design for a building came with some difficult realities in terms of practicality. It is, after all, an art museum, but all the floors are on an angle and all the walls are curved. This makes some people complain that the paintings and art on display are hard to appreciate. But even today people visit the museum as much to experience the building as to see the art on display there.